Gamma globulin vs immunoglobulin

Family of globular proteins

Not to be confused with globin or globular protein.

The globulins are a family of globular proteins that have higher molecular weights than albumins and are insoluble in pure water but dissolve in dilute salt solutions.

Some globulins are produced in the liver, while others are made by the immune system. Globulins, albumins, and fibrinogen are the major blood proteins. The normal concentration of globulins in human blood is about 2.6-3.5 g/dL.

The term "globulin" is sometimes used synonymously with "globular protein". However, albumins are also globular proteins, but are not globulins. All other serum globular proteins are globulins.

Gamma globulin synthesis in liver

Types of globulin

All globulins fall into one of three categories:

Globulins can be distinguished from one another using serum protein electrophoresis.

Globulins exert oncotic pressure.

Their deficiency results in loss of carrier functions of globulins, oedema due to decreased oncotic pressure, and susceptibility to infections due to decreased gamma-globulins (immuno-globulins) leading t

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